Declaring a disease
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Declaring a disease

Declaring a genetic disease, instructions

The National Observatory for Bovine Abnormalities needs your help to identify the appearance of new diseases and to manage them as quickly as possible.

If you witness a congenital defect or with differential expression, whatever its origin or even if its origin is unknown, please describe the case using the on-line ONAB form and send it to the contacts indicated below. We encourage you to contact your veterinarian, a breeding technician or an inseminator. They probably will have experience in declaring cases and will be able to help you.

1. Déclarer l’anomalie

    ≈ on-line genetic disease declaration form

    ≈ download the genetic disease form here .pdf

2. If possible, please take digital photos

   which you can send by email to: contact.onab@inrae.fr

3. Join 1 or 2 tubes of blood EDTA, 1 ear biopsy, or even a piece of tongue taken before rendering - to be frozen before being sent!

In particular for the following diseases:

     At least for the diseases that are the object of a research program currently underway, send 1 or 2 tubes of blood EDTA (purple cap, shake thoroughly to avoid freezing), or an ear biopsy, or a piece of tongue if the animal is dead, along with the declaration form and contact the persons indicated below:

  • Periodic spastic syndrome in Holsteins (specific form available)
  • Colon atresia in Holsteins (specific form available for veterinary samples)
  • Horn defects (fiche spécifique disponible)
  • Cleft palate in Limousine breed
  • Pathological straight-in hocks in Montbeliard breed (specific form available)
  • Dwarfism all breeds
  • Problems with dry-off quarters, mammary glands or teats (specific form available)
  • Facial defects in montbeliard breed (specific form available)
  • Ombilical hernias (specific form available)
  • Arthrogrypose/cleft palate in Charolais
  • Arcing and bending in Normandy breed (specific form available)
  • Vision problem all breeds (specific form available for progressive sight loss in Normandy cattle)
  • Absence of fur, alopecia (specific form available for alopecia at limb extremities in Normandy breed), hypotrichosis, hairless-toothless, etc.
  • Skin problems: black fur follicular dysplasia, dermatosparaxia, ichtyosis…
  • Joint oedema (Hydropisia) in charolaise breed
  • Absence of testicules or cryptorchidism
  • Sexual chromosome defect (discordant phenotypes and genotypes)
  • Agressive behavior (specific form available)

These samples will be used for research programs in order to identify the genetic cause of these declared diseases. By sending these tubes, the breeder agrees to their use for research purposes.

A few references on genetic diseases

  • Special issue "Genetic diseases" published in INRAE Productions Animales 2016,
    volume 29 numéro 5 (in French, abstract in English)
  • Institut de l’Elevage, 2008. Maladies des Bovins, 4ème édition. Editions France Agricole.
  • OMIA : An on-line database of genes, hereditary diseases and traits in over 135 animal species including cattle.

 

Contact

NEW : one address, three recipients! A guarantee to hear back from us :)
contact.onab@inrae.fr

Cécile Grohs  (cecile.grohs@inrae.fr - tel. 01 34 65 24 57) in the laboratory, for a descriptive form with samples

INRAE - Centre IdF Jouy-Antony
UMR de Génétique Animale et Biologie Intégrative
Equipe GBoS
Bâtiment 440, 4 rue Jean Jaurès
78352 Jouy-en-Josas cedex

Rachel Lefebvre
(rachel.lefebvre@inrae.fr)
INRAE - Centre IdF Jouy-Antony
UMR GABI - Equipe GBoS
4 rue Jean Jaurès, Bât. 211
78352 Jouy-en-Josas cedex

Stéphanie Minery (stephanie.minery@idele.fr) for a descriptive form without samples only

Institut de l'Elevage
UMR de Génétique Animale et Biologie Intégrative
Equipe GBoS
Bâtiment 211, 4 rue Jean Jaurès
78352 Jouy-en-Josas cedex

See also

Declaring a genetic diseases is a legal obligation, stated in the December 12, 2013 decree relative to the recording and certification of bovine parentage

Last update of this information: 22 August, 2020
NOR : AGRT1327574A
JORF n°0294 du 19 décembre 2013, Version en vigueur au 01 décembre 2020

Article 6

In application of article D. 653-55 of the French Rural and Maritime Fishing Code, breeders involved in the parentage certification scheme for one or more breeds in their herd: 1. keep a register of private or public, natural or artificial breeding operations, as defined in article R. 653-75 of the French Rural and Maritime Fishing Code, carried out on their farm, and make the corresponding information available to the breeding establishment. 2. Declare all other information stipulated in the national specifications mentioned in article 3 of the present order after the birth of each calf. This information includes data relating to observed diseases.

Modification date: 18 November 2025 | Publication date: 23 January 2012 | By: ONAB